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Good News Also Deserves Attention
The current model of attention has downsides
Apr 16
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John Mandrola
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Good News Also Deserves Attention
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Co-Author Andrew Foy Weighs in on our Industry Payments JAMA Paper
Good morning friends. This is a super short note to alert you that senior author Andrew Foy has posted his opinions on our recent JAMA paper. You may…
Apr 4
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John Mandrola
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Co-Author Andrew Foy Weighs in on our Industry Payments JAMA Paper
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March 2024
Our JAMA Paper on Industry Payments and Sowell's Conflict of Visions
My career in cardiology can be separated into two decade-long blocks. The first decade I practiced like most other cardiologists. I went with the flow…
Mar 31
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John Mandrola
130
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Our JAMA Paper on Industry Payments and Sowell's Conflict of Visions
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Sorry for the paywall on yesterday's post
I apologize for putting yesterday’s post behind a paywall. This is the Substack default and I forgot to change it. The post is here. It is an…
Mar 18
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John Mandrola
15
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Sorry for the paywall on yesterday's post
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Thoughts on Weight-Loss Drugs and Trust in the Scientific Enterprise
An email from a colleague nails the tension regarding use of the new drugs for obesity.
Mar 17
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John Mandrola
39
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Thoughts on Weight-Loss Drugs and Trust in the Scientific Enterprise
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Please everyone, Stop and Think about the NEJM paper on plastics and heart disease
This will be a short post. I have read the NEJM paper on plastics and the risk of future heart events. It is a clever and interesting analysis. It has…
Mar 7
•
John Mandrola
35
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Please everyone, Stop and Think about the NEJM paper on plastics and heart disease
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February 2024
Dear Colleagues ... Wake Up, You Are Being Used
I really don’t like scolds. I have hesitated to write this short piece because it makes me seem like a scold. But I can’t help myself. This week I saw…
Feb 11
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John Mandrola
137
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Dear Colleagues ... Wake Up, You Are Being Used
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January 2024
Trials and Expiration Dates
Three examples of previously beneficial treatments that need to be retested because the clinical situation changed
Jan 31
•
John Mandrola
54
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Trials and Expiration Dates
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The Problem in Science and Medicine is Not at the Tails but In the Middle of the Curve
Vinay Prasad has an excellent post on Sensible Medicine about scientific fraud. He wrote about a recent Freakonomics podcast about bad science. Outright…
Jan 17
•
John Mandrola
104
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The Problem in Science and Medicine is Not at the Tails but In the Middle of the Curve
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Coronary Artery Calcium Scans Are Not the Answer
Medical tests can never be good or bad. The problem is always the humans who misuse the test. For now, though, I argue (again) against using CAC scans
Jan 14
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John Mandrola
114
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Coronary Artery Calcium Scans Are Not the Answer
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Two More Cardiology Highlights from 2023
Randomized controlled trials had a great showing last year.
Jan 10
•
John Mandrola
35
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Two More Cardiology Highlights from 2023
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Cardiology Trials - A New Project for 2024
Along with two other cardiologists, I am co-authoring a special type of cardiology project. It's textbook; but not a normal one.
Jan 1
•
John Mandrola
70
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Cardiology Trials - A New Project for 2024
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